Find information about common, infrequent and rare side effects of Midol Complete Oral. Prozac (fluoxetine) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. Fluoxetine affects chemicals in the brain that may be unbalanced in people with depression, panic, anxiety, or obsessive-compulsive symptoms. Learn about Midol Complete from patients' first hand experiences and trusted online health resources, including dosage, side effects and interactions. 177 discussions on Treato Three days ago my monthly was ending (aka period) bad cramps were over and once a month anyway just for one day….just one day. I use to take midol the blue box called midol complete, but later on upgraded to midol extended because they are the best!!!! Summary. Drug interactions are reported among people who take Midol and Fluoxetine together. This study is created by eHealthMe based on reports of 7 people who take Midol and Fluoxetine from FDA, and is updated regularly. Summary. Drug interactions are reported among people who take Prozac and Midol together. This study is created by eHealthMe based on reports of 13 people who take Prozac and Midol from FDA, and is updated regularly. I take 20 mg of generic Prozac a day, and I was wondering if taking Midol will have any side effects. - Answered by a verified Health Professional - Answered by a verified Health Professional We use cookies to give you the best possible experience on our website. Find patient medical information for Midol Complete Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. What other drugs will affect Midol IB? Ask your doctor before using Midol IB if you take an antidepressant such as citalopram , escitalopram , fluoxetine ( Prozac ), fluvoxamine , paroxetine , sertraline ( Zoloft ), trazodone , or vilazodone. Best Answer: Yes, you can. Everyone seems to totally freak out about taking other medications when you're on Prozac, but in reality, no over the counter medications apart from St John's wort are likely to interact with it.